Basal cell carcinoma (BCC) accounts for 80% of all nonmelanoma skin cancers. Its metastasis is extremely rare, ranging between 0.0028 and 0.55 of all BCC cases. The usual metastasis to lymph nodes, lungs, bones, or skin is from the primary tumor situated in the head and neck region in nearly 85% cases.
Is it common for basal cell carcinoma to metastasize?
Introduction. Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%.
How long does it take for basal cell carcinoma to metastasize?
In one review of 170 cases, the median interval between onset of BCC and metastasis was 9 years, with a range of less than 1 year to 45 years. Despite the long period from onset to metastasis, the tumor behaves aggressively once metastasis occurs.
How often does basal cell metastasis?
While basal cell carcinoma (BCC) is the most common cancer in the United States,1 metastasis (mBCC) is extremely rare, with an incidence of 0.0028% to 0.55%.
Can basal cell carcinoma spread to organs?
The cancer has spread to areas below the skin, such as into muscle, bone, cartilage, or lymph nodes, but only those near the original tumor. It has not spread to distant organs.
How deep does basal cell carcinoma grow?
Superficial BCC mean depths ranged from 0.17 mm on the cheek to 0.40 mm on the foot. Combined superficial and nodular BCC subtype depths ranged from 0.63 mm on the thigh to 1.50 mm on the lip. Nodular BCC depths ranged from 1.36 mm on the eyelid to 1.98 mm on the hand.
What is an aggressive BCC?
Aggressive BCC tends to have no or less pink within the tumor area and absent or few vessels in the central tumor area compared to other BCC subtypes. Superficial BCC typically has the dermatoscopy vascular features of increased pink and relative absence of large diameter vessels.
What is the average size of a basal cell carcinoma?
Santiago et al. researched 306 cases of BCC with an average size of 5.7 mm (range: 5-6 mm). Excision of the tumors using 2, 3, and 4 mm margins achieved complete excision of the lesion, including the subclinical extension area, in 73.9%, 94.4%, and 99% of cases, respectively.
Can basal cell spread to lymph nodes?
The choice of which type to use depends on your own case. In rare cases basal and squamous cell skin cancer can spread to the nearby lymph nodes (bean-size sacs of immune system cells.) Ask your doctor if your lymph nodes will be tested. Basal and squamous cell cancers don’t often spread to other parts of the body.
What is the survival rate for basal cell carcinoma?
The 5-year relative survival for BCC is 100%. This means that, on average, all of the people diagnosed with BCC are just as likely to live at least 5 years after their diagnosis as people in the general population. The 5-year relative survival for SCC is slightly less at 95%.
Has basal cell carcinoma killed anyone?
Basal cell carcinoma is far more common than squamous cell carcinoma. About 80% of non-melanoma skin cancers are basal cell carcinoma. The rate of deaths from these skin cancers have been declining in recent years. About 2,000 people die from basal cell and squamous cell skin cancer each year.
Can basal cell carcinoma invade bone?
Basal cell carcinoma (BCC) is a slow-growing tumor and rarely metastasizes; however, it can occasionally exhibit locally aggressive behavior. Locally advanced BCC has been estimated to account for 0.8% of all BCC cases. Of this small subset of BCC, some have the potential to invade into deep structures, including bone.
What happens if basal cell carcinoma spreads?
Basal cell carcinomas rarely spread (metastasize) to other parts of the body. Instead, they invade and slowly destroy surrounding tissues. When basal cell carcinomas grow near the eyes, ears, mouth, bone, or brain, the consequences of spread can be serious and can lead to death.
What’s worse basal cell or squamous?
Though not as common as basal cell (about one million new cases a year), squamous cell is more serious because it is likely to spread (metastasize). Treated early, the cure rate is over 90%, but metastases occur in 1%–5% of cases. After it has metastasized, it’s very difficult to treat.
Does basal cell carcinoma increased risk of other cancers?
People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for developing of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study by researchers at the Stanford University School of Medicine.