What type of cancer does letrozole treat?

Letrozole is a medicine used for treating breast cancer. It can also help prevent breast cancer coming back. It is mainly prescribed for women who have been through the menopause and have a type of cancer called “hormone-dependent” breast cancer.

Does letrozole stop cancer spreading?

Drugs such as everolimus and letrozole have been shown to be effective at stopping tumor growth either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

What type of breast cancer does letrozole treat?

Letrozole is used treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods) and who have had other treatments, such as radiation or surgery to remove the tumor.

How effective is letrozole for cancer?

Compared with placebo, letrozole significantly improved overall survival in node-positive women by 39% (HR: 0.61; 95% CI: 0.38–0.98; p = 0.04), the only significant survival benefit observed to date in early breast cancer with an AI in a Phase III double-blind, randomized trial [17,18].

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Is taking letrozole considered chemotherapy?

Official Answer. Letrozole is not chemotherapy, it is a type of hormone therapy that is used to treat people with breast cancer that is hormone receptor-positive.

Can I take vitamin D with letrozole?

No interactions were found between letrozole and Vitamin D3.

Can breast cancer come back while on letrozole?

Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back.

What is the success rate of letrozole?

In the intention-to-treat analysis, women who received letrozole alone had a disease-free survival rate of 73.8 percent at 8 years, compared with a rate of 70.4 percent for women who received tamoxifen alone.

Why was letrozole banned?

That study also found no significant difference in the rate of overall abnormalities, but found that congenital cardiac anomalies was significantly higher in the clomiphene group compared to the letrozole group. Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.

Is letrozole an immunosuppressant drug?

siponimod and letrozole both increase immunosuppressive effects; risk of infection. Use Caution/Monitor. Caution if coadministered because of additive immunosuppressive effects during such therapy and in the weeks following administration.

Why do you have to take letrozole for 5 years?

A new trial suggests that extending aromatase inhibitor therapy with letrozole for an additional 5 years may improve disease-free survival and reduce the rate of new contralateral breast cancers in this group of postmenopausal women.

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What foods interact with letrozole?

Foods like Cranberry and Evening Primrose should be eaten when undergoing Letrozole treatment for Paget Disease of the Breast. On the same lines, avoid foods like Caraway and Custard Apple while taking Letrozole treatment for Paget Disease of the Breast.

Is letrozole hormone therapy or chemotherapy?

Letrozole is a hormone therapy. Letrozole is classified as an aromatase inhibitor.

What are the long term side effects of letrozole?

Side effects that are more likely to take a few months to develop and persist long term include:

  • blood changes, such as decreases in white blood cell counts or platelets.
  • edema (swelling that usually affects your hands, feet, legs, or arms)
  • hair loss.
  • high cholesterol.

Can letrozole shrink tumors?

For example, women whose tumors made or ‘expressed’ either of these proteins (ErbB-1 or ErbB-2) appeared to be largely resistant to the effects of tamoxifen, the study showed. Letrozole, however, was very effective in these types of tumors, shrinking them in 88 percent of women.

What are the worst side effects of letrozole?

Side effects of letrozole (Femara)

  • aching or pain in the joints or muscles.
  • menopausal symptoms.
  • low mood and depression.
  • difficulty sleeping.
  • fatigue.
  • osteoporosis.
  • high blood pressure and cholesterol.