How is BSA used to calculate chemotherapy?

How is BSA chemotherapy calculated?

Cancer Chemother Rep 1970;54:225-35.

  1. Equation: BSA (m2) = 0.0235 x Height(cm)0.42246 x Weight(kg)0.51456
  2. Equation: BSA (m2) = 0.024265 x Height(cm)0.3964 x Weight(kg)0.5378
  3. Equation: BSA (m2) = SQR RT ( [Height(cm) x Weight(kg) ]/ 3600 )

Why is BSA used in chemotherapy?

Dosing based on body surface area (BSA) is generally used in an effort to normalize drug concentrations. This is because it is well recognized that measures of many physiologic parameters that are responsible for drug disposition, including renal function and energy expenditure, can be normalized by use of BSA.

How is chemotherapy measured?

Most chemo drugs are measured in milligrams (mg). The overall dose may be based on a person’s body weight in kilograms (1 kilogram is 2.2 pounds).

Why do we calculate BSA?

In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. For many clinical purposes, BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass.

What does 375 mg/m2 mean?

The standard recommended dose of Rituxan is 375 mg/m2 given as an IV infusion weekly for 4 doses. The “/m2” means per meter squared … that is, the actual dose is calculated by the size of the patient.

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How do you calculate body surface area for medication doses?

The most commonly used formula now is that of Mosteller, published in 1987 in The New England Journal of Medicine. According to Mosteller’s “simplified calculation of body-surface area In metric terms” the body surface area = the square root of product of the weight in kg times the height in cm divided by 3600.

When do you use adjusted weight for chemotherapy?

Actual body weight should be used when choosing cytotoxic chemotherapy doses-intravenous or oral-for all patients, regardless of obesity status, especially if the goal of treatment is cure.

What is AUC in chemotherapy?

The most relevant pharmacokinetic parameter for drug exposure is the area under the curve (AUC) of plasma concentration x time following a single dose.

How is chemotherapy cycle calculated?

A cycle is the time between one round of treatment until the start of the next. After each round of treatment you have a break, to allow your body to recover. So if your cycle lasts 4 weeks, you may have treatment on the 1st, 2nd and 3rd days and then nothing from the 4th to the 28th day. Then the cycle starts again.

Which drugs used in chemotherapy?

Chemotherapy Medicines

  • Abraxane (chemical name: albumin-bound or nab-paclitaxel)
  • Adriamycin (chemical name: doxorubicin)
  • carboplatin (brand name: Paraplatin)
  • Cytoxan (chemical name: cyclophosphamide)
  • daunorubicin (brand names: Cerubidine, DaunoXome)
  • Doxil (chemical name: doxorubicin)
  • Ellence (chemical name: epirubicin)

What is a cycle of chemo?

A cycle means that you have a single cancer drug or a combination of drugs and then have a rest to allow your body to recover. You might have some chemotherapy injections over a day or two and then have some time with no treatment. The treatment and rest time make up one treatment cycle.

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How do you use BSA?

Body Surface Area (BSA)

  1. Calculate weight in kilograms: 210 pounds ÷ 2.2 = 95.45 kg.
  2. Calculate height in centimeters: 6 feet, 3 inches = 75 inches x 2.54 cm/inch = 190.5 cm.
  3. Multiply height by weight and divide by 3600. (190.5 cm x 95.45 kg) ÷ 3600 = 5.
  4. Take the square root of 5 = 2.24 m2

What is normal BSA?

Body surface area: BSA. … The “normal” body surface area is generally taken to be 1.7 m2 but, in actual fact, the body surface area depends on more than just height and weight. Other influential factors include the age and gender of the individual. For example: Average body surface area for adult men: 1.9 m2.

What is BSA test?

Body Surface Area or BSA is not a measurement used commonly in fitness assessment, but is a common measure in the medical field and part of the complete body size and composition profile. … equipment required: scales for measuring weight, stadiometer for measuring height, calculator for working out the formula.