What kind of chemo is gemcitabine?

Gemcitabine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. Gemcitabine is classified as an antimetabolite.

What class of chemotherapy is gemcitabine?

How long does treatment take? A cycle (dose) of gemcitabine, with paclitaxel, lasts 21 days. Gemcitabine is given on days one and eight of the cycle. The time between each cycle of treatment gives your body time to recover.

Is gemcitabine an immunotherapy drug?

Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy.

What cancers are treated with gemcitabine?

Gemcitabine, a pyrimidine nucleoside antimetabolite, is one of the most promising new cytotoxic agents. The drug has shown activity in a variety of solid tumors, and has been approved for the treatment of non-small cell lung cancer, pancreatic, bladder, and breast cancer.

How effective is gemcitabine?

Treatment with single-agent gemcitabine achieved clinical benefit and symptoms improvement in 20-30% of patients. While 1-year survival was observed in 2% of 5-fluorouracil (5-FU)-treated patients, it was raised to 18% by single-agent gemcitabine.

What is the difference between gemcitabine and capecitabine?

You have gemcitabine as a drip into your bloodstream (intravenously). Capecitabine is a tablet you take twice a day, after food. You swallow the tablets with water within 30 minutes of finishing a meal.

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How toxic is gemcitabine?

Gemcitabine is associated with a wide spectrum of lung toxicities, ranging from dyspnea 25% of patients to severe pulmonary toxicity in up to 5% of patients.

How long does gemcitabine infusion take?

Gemcitabine is given as an infusion into a vein – you may hear this called a ‘drip’. You will have an infusion of gemcitabine through a cannula. The infusion takes 30 minutes.

When does gemcitabine side effects start?

The following side effects are common (occurring in more than 30%) for patients taking Gemcitabine: Flu-like symptoms(muscle pain, fever, headache, chills, fatigue) Fever (within 6-12 hours of first dose)

Does gemcitabine cause neuropathy?

Gemcitabine monotherapy has not been proved to be associated with the risk of peripheral neuropathy [96]. Side effects exerted on the central nervous system by 5-fluorouracil (5-FU) were reported in 2-5% of patients [97].

Is gemcitabine platinum based?

Platinum based gemcitabine was widely used in the late 1990s and 2000s as a part of phase studies in MPM because of the synergy between gemcitabine and platinum compounds [4–11]. In those studies, 9.6 to 13 months of overall survival time and 12 % to 48 % of the response rates were reported [4–11].

Do you lose your hair with gemcitabine?

Hair loss. You could lose all your hair. This includes your eyelashes, eyebrows, underarm, leg and sometimes pubic hair. Your hair will usually grow back once treatment has finished but it is likely to be softer.

What is the strongest chemo drug?

Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it’s used to treat a wide variety of cancers. Unfortunately, the drug can also damage heart cells, so a patient can’t take it indefinitely.

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What is gemcitabine approved for?

Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to chemotherapy that included an anthracycline drug.

How much does gemcitabine cost?

About Gemcitabine

GEMCITABINE is a chemotherapy drug. This medicine is used to treat many types of cancer like breast cancer, lung cancer, pancreatic cancer, and ovarian cancer. The lowest GoodRx price for the most common version of gemcitabine is around $91.22, 76% off the average retail price of $395.72.