Question: Does vagifem cause cancer?

An analysis of data collected as part of the Women’s Health Initiative (WHI) trial has found that postmenopausal women who use vaginal estrogen have the same risk of invasive breast cancer, stroke, blood clots, endometrial cancer, and colorectal cancer as women who don’t use vaginal estrogen.

Does Vagifem increase risk of cancer?

Evidence suggests that using Vagifem® does not increase the risk of breast cancer in women who had no breast cancer in the past. It is not known if Vagifem® can be safely used in women who had breast cancer in the past.

What are the risks of taking Vagifem?

The most commonly reported side effects of Vagifem® included: headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.

Is Vagifem safe to use long term?

Endometrial safety of long-term (more than one year) or repeated use of local vaginally administered oestrogen is uncertain. Therefore, if repeated, treatment should be reviewed at least annually, with special consideration given to any symptoms of endometrial hyperplasia or carcinoma.

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Can Vagifem cause ovarian cancer?

If you have any further questions on the use of this medicine, ask your doctor or pharmacist. Like all medicines, this medicine can cause side effects, although not everybody gets them. ovarian cancer; blood clots in the veins of the legs or lungs (venous thromboembolism);

Can a pessary cause cancer?

Some studies suggest that long-term (chronic) irritation of the vagina in women using a pessary may slightly increase the risk of squamous cell vaginal cancer. But this is very rare, and no studies have clearly proven that pessaries cause vaginal cancer.

Do estrogen suppositories cause cancer?

Although estrogen replacement had been linked to an increased risk of cardiovascular disease and cancers, a landmark new study demonstrates no rise in risk for women using topical estrogen for relief of genitourinary syndrome.

Is there an alternative to Vagifem?

Vagirux – an alternative to Vagifem both are small pessaries inserted into the vagina. The Vagirux is applicator used to insert the pessary into the vagina is reusable unlike the Vagifem applicator making it more environmentally friendly. 3.

What are the benefits of using Vagifem?

Vagifem® 10 mcg treats the underlying cause of menopause-related vaginal changes by helping to replenish the vagina’s lost estrogen.

What Vagifem® treats.

  • Vaginal dryness.
  • Pain and bleeding during intercourse.
  • Irritation.
  • Soreness.
  • Itching in and around the vagina.
  • Painful urination.

Is Vagifem the same as Premarin?

These contain slightly different forms of estrogen hormones: Vagifem (contains estradiol) – tablet. Estragyn (contains estrone) – cream. Premarin (contains conjugated estrogens) – cream.

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Can I take vagifem once a week?

When to take Vagifem® 10 mcg.

For the first 2 weeks, you’ll use Vagifem® (estradiol vaginal inserts) 10 mcg once daily. After that, you’ll reduce to twice a week, as directed by your health care provider.

Does vagifem make you gain weight?

headache; swelling in your hands or feet, weight gain; breast pain; or. vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding.

Can I use Vagifem 3 times a week?

The usual dosage range is 2 to 4 g (marked on the applicator) daily for 1 or 2 weeks, then gradually reduced to one-half initial dosage for a similar period. A maintenance dosage of 1 g, 1 to 3 times a week, may be used after restoration of vaginal mucosa has been achieved.

Does vagifem get into bloodstream?

More recent studies have confirmed that estrogen in vaginal creams or tablets (Vagifem) is readily absorbed into the body (Annals of Oncology, April 2006; Menopause, January 2009). There are concerns that vaginal exposure to estrogen might increase the risk of breast cancer in susceptible women.

Does Estriol cause cancer?

Vaginal oestrogens and oral estriol seemed safe, even when used for more than five years. The risk associated with long term use of systemic estradiol didn’t vary significantly with the dose. Long term use was associated with both lobular and ductal cancers, and with both early and later stage disease.

Can bioidentical hormones cause cancer?

There is also a concern with the bioidentical oral preparations, as there may be inconsistencies in the quantities of estradiol and other estrogen preparations in compounded preparations. This can lead to an increased risk of venous thromboembolism, as well as increasing the risk of endometrial cancer.

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