Lanreotide (Somatuline Depot Injection) Chemotherapy Drug Information.
What type of drug is lanreotide?
Lanreotide injection is in a class of medications called somatostatin agonists. It works by decreasing the amounts of certain natural substances produced by the body.
How long can you be on lanreotide?
Lanreotide is a long-acting formula, which allows the medication to be slowly released into the body over a 4-week period. The patient typically receives one injection a month at their doctor’s office, with the medication lasting all month in the body.
Is somatostatin a chemotherapy?
Medical treatment includes chemotherapy, somatostatin analogues and alpha interferons. Chemotherapy has been particularly active in patients with high proliferating neuroendocrine tumours such as endocrine pancreatic tumours and lung carcinoids.
Is lanreotide a hormone therapy?
Lanreotide (also known as Somatuline) is a man made (synthetic) version of the natural hormone somatostatin. You might have it as a treatment: for carcinoid syndrome. to control the growth of some advanced neuroendocrine tumours (NETs) of the intestine and pancreas when surgery is not possible.
Can Lanreotide shrink tumors?
PRIMARYS showed that primary treatment with lanreotide Autogel 120 mg every 28 days provides clinically significant reductions (≥20%) in tumor volume in 62.9% of patients at 1 year.
How long can you take somatuline?
The treatment with Somatuline Autogel should be continued for as long as needed for tumour control. The recommended starting dose is 60 to 120 mg administered every 28 days.
How much does Lanreotide cost?
Lanreotide is priced at $7,638 per 28 days or $99,300 per year (January 2020 Medicare Part B average sales price [ASP]–based maximum payment allowance),5 nearly doubling in inflation-adjusted terms over the past decade.
Does Lanreotide cause weight gain?
high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; underactive thyroid symptoms–tiredness, depressed mood, dry skin, thinning hair, decreased sweating, weight gain, puffiness in your face, feeling more sensitive to cold temperatures; or.
Does Lanreotide affect immune system?
Lanreotide Induces Cytokine Modulation in Intestinal Neuroendocrine Tumors and Overcomes Resistance to Everolimus. Somatostatin analogs mantain their major role in the treatment of patients with advanced neuroendocrine tumors (NETs) and have multiple modulatory effects on the immune system.
Is lanreotide A somatostatin analogue?
Lanreotide is a somatostatin analogue. You might have it as a treatment for carcinoid syndrome. Find out about how you have it, possible side effects and important information.
Is octreotide a chemo drug?
Drug type: Octreotide is hormone drug that is used to treat some types of cancer. This medication is classified as a somatostatin analog. (For more detail, see “How this drug works” section below).
What is the difference between lanreotide and octreotide?
Overall, lanreotide had a median satisfaction score of 5.0 compared to a score of 4.0 with octreotide LAR (p = 0.03). Conclusions: Lanreotide was associated with significant reductions in drug-delivery time compared to octreotide LAR, which contributed to an improvement in overall healthcare efficiency.
Does Lanreotide block serotonin?
Lanreotide (lan ree’ oh tide) is a synthetic octapeptide and analogue of somatostatin that is used for its ability to suppress levels and activities of hormones (growth hormone, insulin, gastrin, secretin, glucagon) or active neuropeptides (serotonin, vasoactive intestinal polypeptide [VIP]).
Can Lanreotide cause weight loss?
Headache, muscle/joint pain, dizziness, nausea, vomiting, loose stools, diarrhea, constipation, stomach upset, gas, or weight loss may occur. Pain and irritation at the injection site may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.