Best answer: Can borderline tumors come back?

The main treatment for borderline tumours is surgery. Most women are cured and have no further problems. There is a small risk of the tumour coming back. Very rarely, the borderline tumour cells change into cancer cells.

Can borderline tumors become malignant?

Preoperatively, borderline tumors are often presumed to be either benign or malignant ovarian masses; however, as with other ovarian masses, staging is performed surgically.

Are serous borderline tumors staged?

Results: The majority (78%) of ovarian borderline tumors primarily were encountered and staged by general obstetrician-gynecologists. Overall, 66% of patients had at least 1 staging biopsy performed.

What does it mean when a tumor is borderline?

A borderline tumor, sometimes called low malignant potential (LMP) tumor, is a distinct but yet heterogeneous group of tumors defined by their histopathology as atypical epithelial proliferation without stromal invasion.

Do borderline tumors spread?

Observation is often recommended for borderline tumors because they grow very slowly and even when they spread they are rarely fatal. If the tumor has spread outside the ovary when it is first diagnosed, the surgeon will remove as much of it as possible (debulking).

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Are borderline tumors hereditary?

Many studies of BOT are ongoing, but few are evaluating the hereditary risk. Our study reveals a potential hereditary risk of cancer among BOT patients and suggests that between 3% and 19% of patients may need genetic counseling and confirmative testing.

How common are borderline ovarian tumors?

Borderline ovarian tumors comprise about 15%–20% of all epithelial ovarian malignancies [2, 3] with an incidence of 1.8–4.8 per 100,000 women per year [3–5].

What is the histologic feature that differentiates borderline ovarian tumors from invasive ovarian cancers?

Increase in nuclear/cytoplasmic ratio. Slight to complex branching of epithelial papillae and pseudopapillae. Epithelial budding and cell detachment into the lumen. No destructive stromal invasion – A major component in differentiating malignant from borderline tumors.

What is a good CA 125 number?

Results of the CA 125 test are measured in units per milliliter (U/mL). The normal value is less than 46 U/mL. If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer.

What is Seromucinous borderline tumor?

Seromucinous borderline tumors (SMBTs) are characterized by papillary architecture reminiscent of serous tumors but composed of mucinous epithelium similar to that of the endocervix. These tumors are associated with endometriosis [1.

What does borderline mean in medical terms?

Medical Definition of borderline

(Entry 1 of 2) 1 : being in an intermediate position or state : not fully classifiable as one thing or its opposite especially : not quite up to what is usual, standard, or expected borderline intelligence.

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How fast do ovarian Tumours grow?

According to their analyses, early stage ovarian cancers double in volume approximately every 4 months, whereas advanced-stage tumors double in volume approximately every 2.5 months [6].

Does size of ovarian tumor matter?

When it comes to ovarian cancer, size doesn’t necessarily matter: Smaller tumors are just as likely to be malignant. Unfortunately, symptoms of ovarian cancer are vague, causing women to delay seeking care. Here’s how ovarian tumors of varying sizes have impacted the lives of three women.

Can a benign ovarian tumor become malignant?

Benign ovarian tumors usually grow slowly and rarely become malignant. They include the following: Benign cystic teratomas: These tumors are also called dermoid cysts because although derived from all 3 germ cell layers, they consist mainly of ectodermal tissue.

What is borderline serous cystadenoma?

Borderline tumors fall under ovarian epithelial tumors. They tend to develop in an exophytic growth pattern, on the surface of the ovary, without invading the underlying stroma. Papillary projections are characteristic and may be more of a feature with borderline than malignant serous cystadenocarcinoma of the ovary.

How do you know if an ovarian cyst is cancerous?

Oftentimes imaging tests like ultrasound or MRI can determine if an ovarian cyst or tumor is benign or malignant. They may also want to test your blood for CA-125, a tumor marker, or preform a biopsy if there is any question. High levels of CA-125 may indicate the presence of ovarian cancer.